A system (50) for sensing tire parameters in the remote monitoring and management of a fleet of autonomous vehicles (24) is provided. The system (50) includes at least one autonomous vehicle (24) that is supported by at least one tire (10). At least one sensor (22) is affixed to the tire (10) for sensing tire parameters. Means are provided for communicating data generated by the sensor (22) to a control system on the vehicle (24), and a mobile network (34) receives the sensor data from the vehicle control system. A fleet management server (38) receives the sensor data from the mobile network (34), and means are provided to generate commands for the autonomous vehicle (24) in real time based upon the data generated by the sensor (22). A method for sensing tire parameters in the remote monitoring and management of a fleet of autonomous vehicles (24) is also provided.